GASTRIN RELEASING PEPTIDE (GRP)
The functions of GRP are those:
- Neurocirculating hormone
- Tissue-specific growth factor
Increasing evidence suggests that BLPs and GRPR may play a role in CNS disease, including memory disorders associated with AD and other neurodegenerative disorders.
According to some researchers,
- GRPR (GRP Receptor) is considered as a target for the treatment of cognitive dysfunction.
- GRP plays a role in brain plasticity.
GRP is a signal chemical released during emotional events in the brain.
In mice, GRP has been shown to help control fear response and GRP deficiency can lead to larger and more permanent feelings of fear.
It has been reported that hormones such as cholecystokinin, bombesin,
gastrin-secreting peptide, neuromedin B and glucagon secreted from the digestive system produce saturation signals, and therefore, their nutrient intake is controlled by their influence.
additionally....
Improvement of autism spectrum disorder symptoms in three children by using gastrin-releasing peptide
Neuropeptides and anxiety disorders: bombesin receptors as novel therapeutic targets
